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Leaving Las Vegas … Rich

Report from the Front Lines at TAM and Freedom Fest

By “rich” I mean intellectually, of course, because as all skeptics know, the laws of probability are precisely employed by all Las Vegas casinos to insure that if you play long enough the money in your pocket will end up in their coffers. It is not for nothing that it is called Lost Wages.

Actually, there are two ways to win at gambling. You can do it the way I did after the final session at TAM Sunday: play for a brief period of time and quit when you are ahead. I started with $200 at a $5 minimum Blackjack table. For around 20 minutes I bounced around between $150 and $250 in chips artfully stacked in front of me as I pretended to be a big spender. The inevitable losing streak then kicked in and I was suddenly down below $50, then clawed my way back up to $228 when it was time to go, saving myself from the over-confidence bias that would have, in time, left me with nothing but green cloth beneath my empty palms. (The other way to win at gambling in Las Vegas? Be the owner of a casino.) (continue reading…)

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Burning Man

Can burn patients really be healed from a distance by phone?

A couple of weeks ago I was at a meeting with television producers at a Pasadena, California hotel when I ran into a man named Richard Greene whom I had met last year at the debate that Leonard Mlodinow and I did with Deepak Chopra and others at Chapman University. With him was a woman named Dr. Marja Pronk, whom Greene introduced as someone who can heal burn patients from a distance by phone, and that she learned this skill under the tutelage of one Dr. Philippe Sauvage. Greene was interested in having me test Dr. Pronk while she was in town, but we ran out of time and the protocols and ethical considerations of intentionally burning either people or animals were prohibitive (in my view) and so at present we are still working on how this claim might be tested under controlled conditions. If you have any suggestions on how we might do this while also meeting the ethical requirements of an Institutional Review Board or Ethical Review Board that overseas the ethical treatment of human and animal subjects in experiments, please let me know.

First, I will provide you the background I was provided followed by my own thoughts on what it would take to test such a claim, along with my thoughts in between on Philippe Sauvage, which as you shall see is making extraordinary claims that go far beyond healing burn patients.

Richard Greene sent me this background material:

photo of burn patient

As we discussed, the claims made by Breton “healer” Dr. Philippe Sauvage and his co-workers, including medical Dr. Marja Pronk (http://www.youtube.com/watch?v=sshO4IrvJzI and www.sosburn.info) are astounding and challenge almost every belief we have in Western science. To date there have been approximately 500 who have benefited from this technology in 29 countries (including 46 states in the US). Here, for example, is a video of 22 year old Chris Fleming from Ontario, CA. and some press clippings from Africa: (continue reading…)

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Folk-Wisdom Medicine versus Science-Based Medicine

This article first appeared as an alternative medicine opinion editorial for the American Medical Associations’s Virtual Mentor Journal, Volume 13, Number 6: 389–393, June 2011.

For many years now there has been considerable debate between so-called complementary and alternative medicine (CAM) and mainstream science-based medicine. In reality there is no debate because there is only science-based medicine and everything else that has yet to be tested. Most of CAM falls into this latter category. This does not automatically mean that all CAM claims are false; only that most of them have yet to be tested through the rigorous methods of science, which begins with the null hypothesis that holds that the hypothesis under investigation is not true (null) until proven otherwise. A null hypothesis states that X does not cause Y. If you think X does cause Y then the burden of proof is on you to provide convincing experimental data to reject the null hypothesis.

The statistical standards of proof needed to reject the null hypothesis are substantial. Ideally, in a controlled experiment, we would like to be at least 95–99 percent confident that the results were not due to chance before we offer our provisional assent that the effect may be real. Everyone is familiar with the process already through news stories about the FDA approving a new drug after extensive clinical trials. The trials to which they refer involve sophisticated methods to test the claim that Drug X (say a statin drug) improves outcomes in Disease Y (say cholesterol-related atherosclerosis). The null hypothesis states that statins do not lower cholesterol and thus have no effect on atherosclerosis. Rejecting the null hypothesis means that there was a statistically significant difference between the experimental group receiving the statins and the control group that did not.

In most cases CAM hypotheses do not pass these simple criteria. They have either failed to reject the null hypothesis, or they haven’t even been rigorously tested to know whether or not they could reject the null hypothesis.

What, then, is the pull of CAM for so many people? According to a 2002 survey of U.S. adults conducted by the National Center for Health Statistics and the National Center for Complementary and Alternative Medicine: 74.6% had used some form of complementary and alternative medicine, 14.8% “sought care from a licensed or certified” practitioner, suggesting that “most individuals who use CAM self-prescribe and/or self- medicate,”1 and that the most common CAM therapies used were prayer (45.2%), herbalism (18.9%), breathing methods (11.6%), meditation (7.6%), chiropractic (7.5%), yoga (5.1%), body work (5.0%), diet-based therapy (3.5%), progressive relaxation (3.0%), mega-vitamin therapy (2.8%), and visualization (2.1%).2

A 2004 survey of 1,400 U.S. hospitals found that over 25% offered such alternative and complementary therapies as acupuncture, homeopathy, and massage therapy. According to researchers Sita Ananth of Health Forum, an affiliate of the American Hospital Association, and William Martin, PsyD, of the College of Commerce at DePaul University in Chicago, in a news release: “More and more, patients are requesting care beyond what most consider to be traditional health services. And hospitals are responding to the needs of the communities they serve by offering these therapies.”3

Herein lies one answer to understanding why CAM sells. There is a market demand for it. Why? One possibility is that people are turning to alternative medicine because their needs are not being met by traditional medicine. As the late medical historian Roy Porter was fond of pointing out, before the 20th century this certainly was the case.4 Medical historians, in fact, are in agreement that until well into the 20th century it was safer not to go to a doctor, thus leading to the success of such nonsense as homeopathy—a totally worthless nostrum that did no harm, thus allowing the body to heal itself. Since humans are pattern-seeking animals we credit as the vector of healing whatever it was we did just before getting well. This is also known as superstition, or magical thinking.

Another explanation may be found in examining what CAMers are offering that mainstream physicians are not: TLC. By this I do not just mean a hand squeeze or a hug, but an open and honest relationship with patients and their families that provides a realistic assessment of the medical condition and prospects. People are going alternative because in too many instances physicians have become highly skilled technicians—cogs in the cold machinery and massive bureaucracy of modern HMO medicine.

I witnessed the effect directly over the course of a decade during my mother’s recurring and malignant meningioma brain tumors. She finally succumbed, but in the process I gained a deeper understanding of why people turn to alternative medicine. Don’t get me wrong—my mother’s doctors were brilliant, her care the very best available, and we have no regrets about what might have been. And that’s the point. Even under such ideal conditions I found the whole experience frustrating and unfulfilling: it was nearly impossible to get honest and accurate information about my mom’s condition; neither my father nor I could get doctors to return our calls; misinformation and (usually) no information was the norm; and despite my best efforts, the relationship with her physicians (with one exception—her oncologist whom I befriended), could not have been more detached.

I found it rather telling, for example, that when I identified myself as “Dr. Shermer” I got faster results at the hospital than when I was merely “Mr. Shermer” (a lie of omission, not commission, since I do have a Ph.D.), but I still found it difficult to get calls returned. Even worse, when my mom’s oncologist (one of the country’s best-known and well-respected in his field) called her surgeons, he too heard too many dial tones. If physicians show such a remarkable lack of professional courtesy with their own colleagues, what are the rest of us to expect?

More than anything patients want information. They want to know what is really going on. They don’t want jargon. They don’t want false hope or unnecessary pessimism. Studies show that patients do better when they know in detail all the steps they will have to take in their recovery process—probably because it allows them to anticipate, plan, and pace themselves. Knowledge is power, and physicians are modern-day shamans. Patients want the power that knowledge brings, and that empowerment cannot be given in the 8.5 minutes the average doctor spends per patient per visit. Patients want a relationship with their primary caretaker that allows them to ask the important questions and expect honest answers.

Physicians tend to have monologues when they should be having dialogues. The reasoning process of diagnosis, prognosis, and treatment goes on inside their heads, and what comes out is a glossed telegram of truncated lingo. The physician-patient connection is a one-way street, an authority-flunky relationship top heavy in arrogance and off-putting to anyone with a modicum of self-esteem and social awareness. If I could reduce all this into a single request, it is this: Talk to patients as if they are thoughtful, intelligent people capable of understanding and deeply curious about their condition.

So…we should turn to CAM then, right? Wrong. An even deeper problem is that CAMers lack much medical knowledge and (especially) scientific reasoning, making them dangerous. The 2002 study referenced above found that 54.9% used CAM in conjunction with conventional medicine but did not always tell their primary care physician, thus leading to possibly deadly mixtures of drugs and herbs.1 It is not a matter of everything to gain and nothing to lose by going CAM (even if your doc offers no hope), because quack medicines cost money, cause harm, and, most importantly, take away valuable time that could and should be spent with loved ones in this already too-short of a stay we have with each other.

Besides TLC, the cognitive pull of CAM is anecdotal thinking. Since humans are pattern-seeking animals, we credit whatever we did just before getting well as the vector of healing. If A appears to be connected to B, we assume that it is unless proven otherwise. This is the very antithesis of the science-based system of the null hypothesis. The recent medical controversy over whether vaccinations cause autism reveals the power of anecdotal thinking. On the one side are scientists who have been unable to find any causal link between the symptoms of autism and the vaccine preservative thimerosal, which breaks down into ethylmercury, the culprit du jour for autism’s cause. On the other side are parents who noticed that shortly after having their children vaccinated autistic symptoms began to appear. These anecdotal associations are so powerful that it causes people to ignore contrary evidence: ethylmercury is expelled from the body quickly (unlike its chemical cousin methylmercury) and therefore cannot accumulate in the brain long enough to cause damage, and rates of autism diagnoses did not decline in children born after thimerosal was removed from vaccines.

The anecdotal thinking upon which CAMers rely—even if unconsciously and with the best of intentions—can be particularly dangerous in the hands of those whose intentions are less than ethical. Thus it is that any medical huckster promising that A will cure B has only to advertise a handful of successful anecdotes in the form of testimonials, and the human brain will do the rest. By way of example from the annals of medical quackery, witness the case of John R. Brinkley, one of the greatest medical quacks of the first half of the twentieth century, and his nemesis Morris Fishbein, the quackbusting editor of the Journal of the American Medical Association. Their decades-long struggle that criss-crossed the American heartland throughout the 1920s and 1930s, represents this tension between folk and scientific medicine, well summarized in Pope Brock’s 2008 book Charlatan: America’s Most Dangerous Huckster, the Man Who Pursued Him, and the Age of Flimflam.5

What Brinkley was selling was what all men want—sexual vitality—and he developed a surgical technique that offered the type of firm results that his male clientele so desperately sought: goat testis sewn right into the patient’s scrotum, which he likened to “embedding a marble in an apple.” Come one, come all. And they did, to the tune of $750 per surgery, advertised widely in newspapers (an AMA study revealed that over half of all newspaper advertising at the time was for patent medicines) and the new fangled technology—radio—which Brinkley took to like an evangelist to television. The ads featured testimonials from happy men who proclaimed their restored manhood, and these anecdotes made Brinkley a rich man as it drove customers to his practice. But as his business grew he got careless, performing operations both before and after happy hour, and fobbing off work to assistants whose medical credentials were even shadier than his own (Brinkley graduated from the unaccredited and improbably named Eclectic Medical University of Kansas City). The result was dozens of dead patients.5

This got the attention of the ambitious Morris Fishbein, whose career coincided with the rise of the AMA’s attempt to rein in flimflammery through accrediting medical colleges and licensing practitioners. Fishbein made his public mark in 1923 when the Chicago Daily News sent him to investigate the “Hot Girl of Escanaba” (Michigan), a woman who suffered from a temperature of 115 degrees for two weeks. Fishbein exposed her as a “hysterical malingerer” when he discovered that a flesh colored hot water bottle was employed to elevate rectal thermometer readings. For the next two decades Fishbein pursued the country’s “most daring and dangerous” swindler, as he called Brinkley, until he finally brought him down in a decisive courtroom confrontation.5

Fishbein’s promotion of science-based medicine was heroic in his day, but medical flapdoodle flourishes today on the Internet so every medical association and journal needs a quackbusting Fishbein on its staff, for without such eternal vigilance folk medicine will trump scientific medicine in the minds of patients. And thus it is that skepticism should be our default rule of thumb when it comes to CAM claims.

References

  1. Barnes PM, Powell-Griner E, McFann K, Nahin RL. “Complementary and alternative medicine use among adults: United States, 2002.” Adv Data. 2004;(343):6. http://nccam.nih.gov/news/camstats/2002/report.pdf. Accessed May 17, 2011.
  2. Barnes, Powell-Griner, McFann, Nahin, 12.
  3. Ananth S. Health Forum 2005 Complementary and Alternative Medicine Survey of Hospitals [news release]. Chicago, IL: American Hospital Association; July 19, 2006. And: www.cbsnews.com/stories/2006/07/20/health/webmd/main1823747.shtml
  4. Porter R. The Greatest Benefit to Mankind: A Medical History of Humanity. New York: W.W. Norton; 1999.
  5. Brock P. Charlatan: America’s Most Dangerous Huckster, the Man Who Pursued Him, and the Age of Flimflam. New York: Crown Books; 2008.
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The Immortalist

A Review of Transcendent Man: A Film About the Life and Ideas of Ray Kurzweil. Produced by Barry Ptolemy, Music by Philip Glass, inspired by the book The Singularity is Near by Ray Kurzweil. Digital release March 1, DVD release May 25. This review appeared in Science on April 1, 2011.

cover

Beware the prophet who proclaims the end of the world, the apocalypse, doomsday, judgment day, the second coming, the resurrection, or the Biggest Thing to Happen to Humanity ever will happen in the prophet’s own lifetime. It is our natural inclination to assume that we are special and that our generation will witness the new dawn, but the Copernican Principle tells us that we are not special. Thus, the chances that even a science-based prophecy such as that proffered by the futurist, inventor, and scientistic visionary extraordinaire Ray Kurzweil—that by 2029 we will have the science and technology to live forever—is unlikely to be fulfilled.

Transcendent Man is Barry Ptolemy’s beautifully crafted and artfully edited documentary film about Kurzweil and his quest to save humanity. If you enjoy contemplating the Big Questions in Life from a scientific perspective, you will love this film. Accompanied by the eerily haunting music of Philip Glass who, appropriately enough, also scored Errol Morris’ film The Fog of War—about another bigger-than-life character who thought he could mold the world through data-driven decisions, Robert McNamara—Transcendent Man pulls viewers in through Kurzweil’s visage of a future in which we merge with our machines and vastly extend our longevity and intelligence to the point where even death will be defeated. This point is what Kurzweil calls the “singularity” (inspired by the physics term denoting the infinitely dense point at the center of a black hole), and he arrives at the 2029 date by extrapolating curves based on what he calls the “law of accelerating returns.” This is “Moore’s Law” (the doubling of computing power every year) on steroids, applied to every conceivable area of science, technology and economics.

Ptolemy’s portrayal of Kurzweil is unmistakably positive, but to his credit he includes several critics from both religion and science. From the former, a radio host named Chuck Missler, a born-again Christian who heads the Koinonia Institute (“dedicated to training and equipping the serious Christian to sojourn in today’s world”), proclaims: “We have a scenario laid out that the world is heading for an Armageddon and you and I are going to be the generation that’s alive that is going to see all this unfold.” He seems to be saying that Kurzweil is right about the second coming, but wrong about what it is that is coming. (Of course, Missler’s prognostication is the N+1 failed prophecy that began with Jesus himself, who told his followers (Mark 9:1): “Verily I say unto you, That there be some of them that stand here, which shall not taste of death, till they have seen the kingdom of God come with power.”) Another religiously-based admonition comes from the Stanford University neuroscientist William Huribut, who self-identifies as a “practicing Christian” who believes in immortality, but not in the way Kurzweil envisions it. “Death is conquered spiritually,” he pronounced.

On the science side of the ledger, Neil Gershenfeld, director of the Center for Bits and Atoms at the Massachusetts Institute of Technology, sagely notes: “What Ray does consistently is to take a whole bunch of steps that everybody agrees on and take principles for extrapolating that everybody agrees on and show they lead to things that nobody agrees on.” Likewise, the estimable futurist Kevin Kelly, whose 2010 book What Technology Wants paints a much more realistic portrait of what our futures may (or may not) hold, asks rhetorically “What happens in 40 years from now and Ray dies and doesn’t have his father back? What does all this mean? Was he wrong? Well, he was right about some things. But in my observation the precursors of those technologies that would have to exist simply are not here. Ray’s longing for this, his expectation, is heartwarming, but it isn’t going to happen.” Kelly agrees that Kurzweil’s exponential growth curves are accurate but that the conclusions and especially the inspiration drawn from them are not. “He seems to have no doubts about it and in this sense I think he is a prophetic type figure who is completely sure and nothing can waiver his absolute certainty about this. So I would say he is a modern day prophet…that’s wrong.”

Transcendent Man is clearly meant to be an uplifting film celebrating all the ways science and technology have and are going to enrich our lives. I don’t know if it is the music or the cinematography or the subject himself, but I found Transcendent Man to be a sad film about a genius who has been in agony since the premature death of his father at age 58. Fredric Kurzweil was a professional musician who Ray’s mother says on camera was never around while his charge was growing up. Like father like son—Kurzweil’s own workaholic tendencies in his creation of over a dozen companies starting when he was 17 meant he never really knew his father. As the film portrays the tormented inventor, Kurzweil’s mission in life seems more focused on resurrecting his patriarch than rescuing humanity.

An especially lachrymose moment is when Kurzweil is rifling through his father’s journals and documents in a storage room dedicated to preserving his memory until the day that all this “data” (including Ray’s own fading memories) can be reconfigured into an A.I. simulacrum so that father and son can be reunited. Through heavy sighs and wistful looks Kurzweil comes off not as a proselytizer on a mission but as a man tormented. It is, in fact, the film’s leitmotif. In one scene Kurzweil is shown wiping away a tear at his father’s gravesite, in another he pauses over photographs and looks longingly at mementos, and in another cut at the beach Kurzweil recalls the day his father “uncharacteristically” phoned him just days before his death, as if he’d had a premonition. Although Kurzweil says he is optimistic and cheery about life, he can’t seem to stop talking about death: “It’s such a profoundly sad, lonely feeling that I really can’t bear it,” he admits. “So I go back to thinking about how I’m not going to die.” One wonders how much of life he is missing by over thinking death, or how burdensome it must surely be to imbibe over 200 supplement tables a day and have your blood tested and cleansed every couple of months, all in an effort to reprogram the body’s biochemistry.

There is something almost religious about Kurzweil’s scientism, an observation he himself makes in the film, noting the similarities between his goals and that of the world’s religions: “the idea of a profound transformation in the future, eternal life, bringing back the dead—but the fact that we’re applying technology to achieve the goals that have been talked about in all human philosophies is not accidental because it does reflect the goal of humanity.” Although the film never discloses Kurzweil’s religious beliefs (he was raised by Jewish parents as a Unitarian Universalist), in a (presumably) unintentionally humorous moment that ends the film Kurzweil reflects on the God question and answers it himself: “Does God exist? I would say, ‘Not yet.’” Cheeky.

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Cell Phones and Cancer

Ever since the publication of physicist Dr. Bernard Leikind’s article in Skeptic (see eSkeptic for June 9, 2010) and my subsequent column in Scientific American in which I cited Leikind’s arguments (both of which were skeptical of claims that cell phone use causes brain cancer), we have been inundated with letters disputing our skepticism. The letters come in a variety of flavors, so what follows are Dr. Leikind’s responses to the critics that he identifies by their email names. My own response to critics will appear in the next issue of Scientific American, so in the meantime I defer to Dr. Leikind’s responses below, as well as to the SkepDoc Harriet Hall, M.D. along with oncologist Dr. David Gorski, both of whom blog at ScienceBasedMedicine.org, which covers the ongoing controversy over cell phones and cancer.

For example, when I queried her on my critics, Dr. Hall responded to me:

I agree that it is premature to say that cell phones “can’t possibly” cause cancer, although Leikind is correct to say physics shows they can’t possibly do it by the mechanisms that have been commonly proposed. The fact remains: there is no good evidence that cell phones do cause cancer. And so far I’m not convinced by the proposed mechanisms by which they might cause cancer. The radiation/mutation and tissue heating explanations have pretty well been debunked. I’m going to continue to think that cell phones don’t cause cancer — and that there is a high probability that the kind of radiation they emit “can’t” cause cancer — until I see something much more convincing in the way of evidence. If they do somehow cause cancer, studies to date have established that any effect can’t be a very large one. Any potential cancer risk pales against the high risk of accidents from using them while driving, and against the convenience and safety effects of having instant communication.

And I asked Dr. Gorski as well, and he responded to me thusly (with links to further reading):

Basically, as I said, the article is correct in dubbing the idea that cell phone radiation causes cancer as very, very improbable, but I thought Leikind went too far in declaring it “impossible” based a priori on physics because, quite frankly, he completely ignores newer biological understanding of mechanisms of carcinogenesis. As I said in my post, I do not believe that cell phones cause cancer. I consider it highly unlikely and implausible. I do think, however, that declaring it “impossible” is premature. More reading from ScienceBasedMedicine.org:

http://www.sciencebasedmedicine.org/?p=84
http://www.sciencebasedmedicine.org/?p=8
http://www.sciencebasedmedicine.org/?p=3073
http://www.sciencebasedmedicine.org/?p=3666

And, here’s my explanation on just how complex cancer is:

http://www.sciencebasedmedicine.org/?p=4832

Finally, Dr. Leikind sent me this wonderful general response to the critics, which I happen to agree with and will be interested in hearing from readers about this ongoing controversy:

It interests me that so many readers see “microwaves from cell phones cannot cause cancer” and understand us to be saying “there are no physiological effects from microwaves.” But our message is not that there are no physiological effects, but that we (the appropriate scientists and engineers) know exactly what the physiological effects of absorbing microwaves are. And those effects cannot cause cancer, and we know this because there are many identical but more powerful similar effects, such as exercise. No one thinks that exercise causes cancer. I also find it persuasive that no one is concerned about cell phone microwaves causing skin cancer. But the radiation is more intense in our hands, ears, and scalp than it is in brains or optic or auditory nerves, and skin cells reproduce many times more frequently than any glial brain cells, and even many more times more frequently than any neuron cells.

Dr. Leikind’s responses to the posted critiques of my and his claims follow:

GreenMind suspects that I may have ties to the cell phone industry. I use an old model Motorola RAZR V3 cell phone and pay T-Mobile about $40 per month for my cell phone service. I would be happy to earn some money from my investigation and writing about cell phones and cancer.

The precautionary principle draws passionate support from public health care professional, Dr. Martin Donohoe. In the case of cell phone microwave radiation, scientists have already done the appropriate research. We know exactly what happens when any material, including living tissue, absorbs microwave radiation. The microwave energy appears as additional shaking, jostling, rattling and rolling of the molecules. In a living human being with her powerful temperature control mechanisms functioning and her blood flowing, we know that there is no potential for microwave radiation from a cell phone to cause significant, widespread or irreparable harm. Therefore, the precautionary principle does not apply. The situation is different when someone invents a new chemical. The precautionary principle would apply to eating cell phones but not to talking on them. It would not apply to texting while driving because the harmful potential is well known.

Freedom for All and dideldum worry about power levels and heating. A cell phone emits about a watt of microwave radiation. Some of that power enters the user’s hand, ear, scalp, skull, and brain and other tissues. To produce this watt of microwave radiation, the cell phone’s electronics must convert somewhat more than a watt of power from its batteries. The excess power and all of the power that goes to operate the circuitry of the phone appears as a temperature increase in the phone. The phone may feel warm. This energy transfers to the user’s hand or ear. Some may transfer to the environment by infrared radiation or convection. This energy does not cause cancer. The temperature increase in the human brain from absorbed cell phone microwave radiation is so small that many researchers mistakenly believe that there are non-thermal effects. The temperature never reaches the various potentially harmful temperatures that Freedom cites.

GreenMind questions Dr. Shermer’s and my statement that there is no known mechanism by which cell phone microwaves might cause cancer. I claim more than that there is no known mechanism. I assert that there is no unknown mechanism.

To summarize, here is the proof. We know exactly what happens to the cell phone microwaves the body absorbs. The energy transfers from the radiation to jostling, jiggling, vibrating and twisting of the molecules. From there, the energy enters to flowing blood, reaches the entire body, and moves to the environment. If the power flow is large, the transfer to the environment will occur primarily by the evaporation of sweat. For the watt or less absorbed from cell phones, the transfer will occur by small changes to the flow of blood to the body’s surface causing slight increases in radiation, conduction, and convection to the environment. There is little temperature increase in a living human being from cell phone microwaves. We know many other processes and effects that produce exactly the same effects at much greater energy and power levels, and all of these are safe and do not cause cancer. Exercise is one such process. Wearing a ski cap is another.

Any researcher who proposes a mechanism by which cell phone radiation might trigger or enhance carcinogenesis is welcome to do so, but must begin with the process described, and also explain why much larger, but otherwise identical processes, do not trigger the proposed mechanism. This thought informs my consideration of the many real and supposed physiological effects of microwave radiation cited by readers.

In the following, I use colloquial language but I could have used the technical terms. Knowledgeable scientists will recognize what these are. I mention specific readers in these notes, but often other readers made similar points.

Richard2010 correctly asserts that it might be possible to modify the complicated and lengthy process by which an initiating incident leads to cancer. He says that microwaves might influence any of the intermediate steps that do not involve breakage of DNA. The only means by which cell phone microwave radiation might influence those steps is through the jiggling, jostling, rocking and rolling that occur when the organism’s thermal control system is functioning. Test tube experiments that do not reproduce the stable temperature conditions in a living organism, however, are not relevant. While some can imagine putative carcinogenic mechanisms from electromagnetic radiation, the only forms of electromagnetic radiation that cause cancer, ultraviolet, X-rays, and gamma rays, operate by breaking chemical bonds in DNA.

Megahurtz, Richard2010, and many other readers assert that microwaves have physiological effects. Some readers cite Russian studies, well known to researchers in this field. Western scientists could not replicate the Russian studies, and do not credit them. Readers point to therapeutic methods. Every therapeutic method that involves microwaves begins with the process I describe. Therapeutic use of microwaves always involves heating tissues.

Monastralblue asserts that microwaves modify chemical bonds or transfer molecules from one quantum state to another nearby state without breaking the bonds. Quantum states of molecules that differ by such a small amount of energy that a microwave photon might cause a transition from one state, the supposedly safe one, to another, the supposedly bad one, will be virtually equally populated in the living organism because of the random shaking, rattling, and rolling of the organism’s molecules. The supposedly bad state will not be empty. If population of the supposed state were bad in some way, carcinogenic or cancer enhancing, then the state would be doing its dirty work at all times.

fscr37 says that Dr. Shermer and I have unstated assumptions and implies that these may be unjustified. The primary scientific assumption that pertains to the question of cell phones and cancer is that the laws of physics apply to biological systems, to organisms, just as they apply to anything else.

The various speculative models, such as the resonance effects to which fscr37 refers, are unphysical and unbiological because they neglect to consider the environment in an organism when they supposedly occur. The energy exchange time, the time it takes for a molecule to transfer energy within its own modes of oscillation or with its neighbors, is about a hundred quadrillionths of a second, 10-13 seconds. This is the result of direct measurements. The oscillation periods of microwave radiation are about a hundred trillionth of a second, 10-10 seconds. That is, molecular jostling will interrupt any buildup of energy by any individual molecule or bond long before the processes frscr37 cites might develop.

Iward notes that the risk that a cell may become cancerous relates to the rate at which it divides. In the brain, for example, neurons divide rarely, if at all, while glial cells divide more often. In adults, brain cancers are gliomas, not neuromas. If there were some effect of microwaves on carcinogenesis related to the division rate of cells, we’d expect that the microwaves might cause skin cancer in phone users’ hands, ears, and scalp. The skin cells divide much more rapidly than any brain cells, and the intensity of the radiation is higher in these skin cells than in any brain cells. Cell phone radiation does not cause skin cancer, and no one fears that it might.

Iward, hereticoftruth, Mark Pine guess that cell phone microwave radiation might have chemical effects other than breaking DNA molecules and refer specifically to denaturing of enzymes. Large, complex biological molecules (and small ones too) take on their shapes through a combination of strong covalent bonds and many weaker chemical bonds, such as hydrogen bonds, van der Waals bonds, and others. Denaturing a molecule refers to the process by which the molecule assumes another form, denaturing. It assumes the denatured form by breaking bonds, mostly weak ones. A cell phone’s microwave radiation absorbed by a living human being cannot denature any biological protein or enzyme unless that radiation can substantially increase the tissue’s temperature in the living organism. High power microwave radiation, much higher than from any cell phone, may damage the cornea in this way. Cooking tissue is bad, but does not cause cancer.

Rivk, tomerg compares microwave cooking with absorbing microwave radiation from a cell phone. Sending microwave power into a roast in a microwave oven causes the temperature of the meat to rise. Sending the same microwave power into a living human being causes the person to sweat with little temperature increase. Dr. Eleanor Adair and others have done this experiment many times. Microwaving a human being causes sweat, not cancer. Can readers guess the difference between a cut of meat and a human being?

Microwaving a person with power levels similar to those of a microwave oven is safe and does not cause cancer. It is not a good idea to microwave a man’s testicles because they prefer temperatures lower than core body temperature. It is a bad idea to microwave your cornea or lens because they have little or no blood supply to provide cooling.

Kiya, jschunke, and pradhangegeorge say that they and other people are hypersensitive to electromagnetic radiation and cite personal experience of these effects from their cell phone use. There is no such thing as electromagnetic sensitivity. It is an imaginary ailment. All double blind tests show that no one can tell if a cell phone or cell phone tower is radiating except through the usual human senses, such as looking at the screen or holding the phone and noting that it is warm. There have been many amusing reports of locals developing vague symptoms when the phone company installs a tower, symptoms that disappear when investigation reveals that the company has not yet installed the amplifiers. Perhaps Kiya would be less prone to headaches if he or she were to choose less annoying people to talk to.

Richard2010 refers to non-thermal effects of microwave radiation. There are none in living organisms, in humans. This fact has not prevented mistaken researchers from doing studies and publishing about non-thermal effects. These researchers mistake the fact that they do not observe a temperature increase with something non-thermal taking place. By their definition, an ice cube melting in a glass of tea or water boiling would be non-thermal effects, but they are thermal effects. Every effect of cell phone microwave radiation must be a thermal effect because the absorbed energy goes into shaking, wiggling, rocking and rolling of the molecules. None of the energy goes anywhere else. If this causes changes to the blood-brain barrier, just to choose one example, then plenty of other things would also cause changes to the blood-brain barrier, such as wearing a ski cap. Wearing a ski cap is safe as long as it doesn’t cover your eyes.

Islesin refers to a comment in Microwave News. This journal has long added to the public’s fears of imagined harm from electromagnetic fields. Scientific American readers may remember the kerfuffle about potential harm from high voltage power lines and household appliances. Microwave News was on the wrong side of that issue too.

On the Internet I am often known as Left Coast Bernard. I say to my neighbor, CaliforniaJoe, that photons are the chunks of energy that carry all forms of electromagnetic radiation, not just visible light.

Agdavis comments on the units in Dr. Shermer’s column, which come from my Skeptic magazine essays. Chemists like to use kJ/mol, kilojoules per mole, which is an energy density, because they like matters relevant to test tube quantities. Using kJ/mol to refer to the energy in a chemical bond is telling us how much energy is in an Avogadro number of bonds, 6 X 1023. An Avogadro number of things is known as a mole, abbreviated mol. A watt-hour is a unit of energy (not a watt per hour); Joules. Physicists would prefer to use a density, just as chemists do. They would refer to Joules/bond or Joules/molecule, while the chemists like Joules per mole, a much larger, test tube sized number. Another reader confuses a mole of cell phones with a mole of photons from a cell phone. Comparing the energy in a mole of chemical bonds with the energy in a mole of microwave photons is correct thinking because it is also comparing the energy in a single bond with the energy in a single photon. The physical effect is, as always, one photon to one bond. Microwave photons do not have sufficient energy to modify any chemical bond, strong or weak.

Monastralblue comments upon safety factors. Here is the way, roughly speaking, that the appropriate organizations establish safety factors for non-ionizing radiation. Since it is a well-established fact that this radiation transfers its energy into tissues as additional shaking, rattling, and rolling, the safety committees find the lowest detectable power level that produces a detectable temperature change, not the lowest level at which some harm occurs. Then they divide this level by 10 or 100. This becomes the official safe level. Exceeding the safe level only means that some temperature increase might be noticed, not that any harm would occur.

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